There has been a growing interest in the study of socioeconomic residential segregation over the last years in Latin America, mainly as a consequence of the evident increase in the social inequalities and privatization processes that have taken place in the cities of the region. Whereas most empirical research has tended to document this phenomenon in large cities, this paper aims to contribute to this field focusing the study in intermediate cities. Based on data retrieved from census microdata, the paper explores social segregation within the urban space of Cordoba as registered in 1991, 2001 and 2008 in terms of spatial concentration and social homogeneity. Furthermore, through the implementation of spatial autocorrelation measures, it is analyzed how such segregation is expressed in the urban space.